Bimzelx is a humanized IgG1 monoclonal antibody designed to target the IL-17A and IL-17F cytokines, which are known to play key roles in immune and inflammatory cascades
Data extraction and management Data were extracted independently by JFA, CK, and AS
Biomed Chromatogr 27:13871397
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Another bioactivation pathway involves aromatic oxidation para to the aniline nitrogen to form 110 and then the quinone imine 111 that can be captured by GSH to form adduct 112 (Fig
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