It's a sprawling and powerful regulatory network involved in a surprising number of physiological processes, including skin pigmentation, inflammation, sexual function, appetite, and energy homeostasis
Co-IP results also revealed that SIRT1 interacted with the active form of ATF6 and promoted its deacetylation, resulting in the downregulation of ATF6 expression in TGF-1-treated HK-2 cells
We conduct GSA with Partial Rank Correlation Coefficient (PRCC), which is a global method where all input factors (model parameters and/or initial conditions) are varied simultaneously using latin hypercube sampling
The effect of inosine in adipocytes was shown to be exerted through the activation of PKA which in turn enhances fat metabolism via increased UCP-1 activity
(2000) Assessment of growth parameters and life span of GHR/BP gene-disrupted mice
PABA/NO is catalytically activated by GST releasing NO that elicits antitumor activity both in vitro and in vivo [191]