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Methods Study Design and Population SURMOUNT-2 (NCT04657003) was a 72-week, multicenter, randomized, double-blind, phase 3 clinical trial that evaluated the safety and efficacy of 10 and 15 mg tirzepatide compared with placebo among adults (18 years or older) with a BMI of 27 kg/m 2 or higher and a T2D diagnosis [12]

J Biol Chem 285:61186126 Turrens JF (2003) Mitochondrial formation of reactive oxygen species

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However, one of the papers authors said yesterday it would be published in a second journal and possibly in others

Incretin mimetics address a key deficiency in T2DM by mimicking the effects of hormones called incretins, which stimulate insulin secretion after meals

In addition, both alcohol and Ozempic may contribute to dehydration