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Moreover, there was a trend toward a liraglutide-induced decrease in the expression of other markers of fibrosis examined in both male and female SKO mice, although these failed to reach statistical significance ( Figures 3E, F )

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A study with infusion of exenatide in T2D patients with chronic heart failure reduced the pulmonary capillary wedge pressure and increased both inotropism and chronotropism [73]

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This raises the question of whether some patients might require longer treatment to sustain weight loss