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Revealing the tissue-level complexity of endogenous glucagon-like peptide-1 receptor expression and signaling

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54 In contrast, when animals were treated with tert-butylhydroperoxide to induce LPO-mediated liver injury, extensive LPOindicated by a 12- to 30-fold increase in these LPO parameterswas necessary to even cause moderate liver injury

That would materially change long-run dosing math and is worth watching as the Q2 to Q3 2026 TRIUMPH-1 and TRIUMPH-2 readouts arrive