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Haas M, Brandl B, Neuhaus K, Wudy S, Kleigrewe K, Hauner H, Skurk T

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This regulatory behavior is why BPC-157 is often safer than traditional vasodilators, which only move the needle in one direction

These small changes reduce new pigment formation so niacinamide can focus on clearing existing discolouration faster

In contrast, NSAIDs and steroids blunt multiple pathways at once, which is effective for acute inflammation and pain control but can disrupt tissue repair or allow infections to advance

For people who have B12 deficiencies or malabsorption problems, these supplements are particularly beneficial