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Within 24 to 48 hours, most patients report noticing reduced hunger and earlier feelings of fullness during meals

Although numerous anti-depressive treatments are available, 30% of patients diagnosed with depression do not experience positive therapeutic effects with these therapies (Al-Harbi, 2012)

According to functional magnetic resonance imaging, anticipatory food reward the anticipated pleasure of eating certain meals is reduced when GLP- 1 R is activated [110, 111]

Coffee may worsen common Wegovy side effects such as nausea (affecting 20-44% of patients) and abdominal discomfort, particularly during dose escalation

Medication combinations require special attention

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