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[DOI] [PubMed] [Google Scholar] 297.Gonzlez-Hedstrm D., de la Fuente-Fernndez M., Priego T., Martn A., Amor S., Lpez-Caldern A., Inarejos-Garca A., Garca-Villaln .L., Granado M

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Identified cellular targets through which PKA activation produces a bronchodilator effect include: MLCK: Phosphorylation of myosin light chain kinase (MLCK) by cAMP-dependent protein kinase (PKA) decreases the affinity of the kinase for Ca2+ and calmodulin , resulting in a decrease in MLCK activity

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