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Characteristic features and pathophysiology A higher incidence of ASD in the offspring has been linked to maternal use of pharmaceutical medications, particularly in the first trimester of pregnancy, such as thalidomide, valproic acid, and antidepressants (primarily selective serotonin reuptake inhibitors

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Kraiss JT, Wijnen B, Kupka RW, Bohlmeijer ET, Lokkerbol J

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