[6] Absolute contraindications include hypercalcaemia, hypervitaminosis D, idiopathic infantile hypercalcaemia, or documented hypersensitivity to vitamin D or components of the oil vehicle because additional vitamin D would worsen calcium overload or provoke severe allergic reactions
In addition, fewer semaglutide-treated patients experienced deterioration in NYHA functional class (2.09% versus 5.24%, respectively
Cardiovascular and mortality outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a meta-analysis with the FREEDOM cardiovascular outcomes trial
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In our recent article about GLP-1s, Angela Meadows, Louise Adams and I created tables for tirzepatide and semaglutide that show the topline results, adverse events, and weight loss for each of the phase 3 placebo controlled weight loss trials, you can find them in the supplemental materials here