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doi: 10.1038/s41591-023-02260-4

Another case series enrolled 30 Chinese women with melasma, who took 25 mg pycnogenol three times daily for 30 days, leading to a 32% mean area reduction and a 22% intensity reduction of facial melasma [86]

Our experienced infusion nurses use gentle techniques to minimize discomfort

These collective findings demonstrate that VPA exposure induces systemic oxidative stress, characterized by concurrent antioxidant depletion (CAT, GSH-Px, GSH, SOD) and elevation of oxidative damage markers (MDA, T-NOS, NO)

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However, high-dose or prolonged unregulated use has been associated with liver stress in some cases