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Decreasing the conductance of voltage-dependent potassium channels, Kv1.3, is the possible ionic mechanism of GLP-1-induced enhancement of MC excitability (Thiebaud et al., 2016)

Ceasing this medication without consulting your doctor can increase blood sugar levels, increasing the risk of severe complications

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Using the right methods, you can stay on track and keep feeling strong, full of energy, and confident in managing your health

The SURMOUNT-4 trial demonstrated that patients who discontinued tirzepatide after achieving weight loss regained significant weight compared to those who continued treatment, though not all weight loss was reversed during the study period

Communicate openly with your partner