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Some experimental results suggest significant increases in circulating IGF-1, which is thought to act as a downstream mediator of growth hormone activity
PubMed ReviewGrowth-hormone peptide evidence2001 The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced decrease in bone formation Preclinical context that should not be overstated as consumer clinical evidence
D., Kwon, D
But enthusiasm should be tempered by caution
The combination of better sleep quality and optimized GH signaling creates conditions for improved cognitive performance that become more apparent as the protocol continues
The trials measured the big changes at 26 weeks, so patience matters
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