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It requires fewer doses than liraglutide, which is a daily injection

Congratulations to Rob Myers, MD, the OrsoBio team, investigators, patients, and all collaborators on these impressive TLC-2716 results shared at #ENDO2026

A preclinical study conducted in diabetic mice revealed that liraglutide reduced AF and prevented atrial remodeling in T2DM model mice [8]

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Securing substantial funding for large-scale clinical trials will be a major determinant of its future

For example, administration of metformin (1000 mg) via a nasoluminal catheter into the ileum, a region of the gut that is rich in L cells did not elicit any GLP-1 response over a 1 h period in patients with type 2 diabetes [8]