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313,314 In one study, OA was induced in rats by injecting MIA into the knee joint, mimicking the pathological changes of human OA

GLP1RA improve blood pressure and reduce CV event risk, likely through central and peripheral autonomic regulation, increased natriuresis, and the presence of these genes in CV tissues (e.g., endothelial cells, vascular smooth muscle cells, resistance arteries) 53

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