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It may occur by enzymatic mechanisms involving lipoxygenases (LOXs), cyclooxygenases (COXs), and ACSL4, or through nonenzymatic processes driven by free radicals [63]

Log transformation was performed as needed to meet the normality assumption

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MiR-122 was the first miRNA identified as tissue-specific, and it is the most abundant in liver involved in lipid metabolic reprogramming 83

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