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doi: 10.1073/pnas.0437870100 79 HsiehJ.NakashimaK.KuwabaraT.MejiaE.GageF

That left it with another oral drug that targets gastric inhibitory peptide (GIPR), PF-07976016, in phase 2

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Future therapies may focus on the simultaneous blockade of these checkpoints, thereby disrupting the multifaceted mechanisms by which MDSCs impair immune cell function and enhance the immune response within the TME (Fig