4 Unlike bioavailable forms of B12 like methylcobalamin, cyanocobalamin occurs only in trace amounts in the body, usually from cigarette smoking or other sources of cyanide
Products made from human plasma may contain infectious agents, such as viruses, and, theoretically, the Creutzfeldt-Jakob Disease (CJD) agent that can cause disease
Importantly, these levels were still lower than those reported in the non-inducible liver-specific Gclc KO mouse strain 30
These findings suggest simple measures, such as dietary supplementation, could be used to correct glycine deficiency
WA wrote the paper
The honest caveat: the only human results come from uncontrolled protocols that combine copper peptides with minoxidil and dutasteride, where the copper peptides independent contribution cannot be separated and the authors themselves note the lack of a control arm (Kuceki et al., 2025)