However, before the onset of clinically diagnosable motor symptoms, most patients experience several non-motor symptoms, including depression, apathy, dementia, rapid eye movement (REM), sleep behavior disorder (RBD), and GI-associated disorders, including reduced gastric emptying and constipation (Seppi et al., 2011
The United States has one of the largest healthcare systems in the world with thousands of hospitals and specialized clinics
It promotes repair of muscles, ligaments, and connective tissue while supporting gut health
This is significantly more than what is typically seen with other weight loss medications
What TRANSCEND-T2D-1 doesn't capture is body composition quality: did the 16.8% reduction preserve lean mass, or does the triple agonist pathway sustain FFM protection seen with dual incretins
Aims: We have previously characterized the augmented myocardial functional response to GLP-1 agonism