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doi: 10.1038/ng1054 29 BauerJCurtinJAPinkelDBastianBC

PubMed, Dron, Jacqueline S., and Robert A

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While GLP-1 RAs are effective for sustaining weight loss, they do not appear to significantly improve physical fitness outcomes in the absence of exercise

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At 12 weeks, Retatrutide averages 8.7% weight loss compared to Semaglutides 5.9%