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Since the cardinal feature of type 4 RTA is hyperkalemia, in the presence of normal urine acidification, the disorder is more appropriately identified as renal tubular hyperkalemia

This chemical interdependence is a key reason why both are formulated together in a single IM dose

Standard oral glutathione may simply lack sufficient bioavailability for measurable effect regardless of dose or duration

Neuropharmacol 41 (5), 151155

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