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Severe caloric restriction depletes these reserves, whilst hormonal changes from rapid weight loss compound the effect by altering thyroid function and increasing cortisol levels, further disrupting normal follicular activity

The dose magnitudes differ (TB-500 protocols typically call for 2-5 mg per injection), but the math remains unchanged

Pharmacol Ther 25:127205 Grandvuillemin A, Rousseau T, Laurent N, Meyer F, Lebouvier M, Disson-Dautriche A (2009) A case of sexual ambiguity under tamoxifen during pregnancy

Cefalu WT, Buse JB, Del PS, et al

Grothe, J., Riethmller, J., Tschurtz, S

However, the slow digestion can conflict with semaglutide-delayed gastric emptying, so start with half a serving and assess tolerance