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However, because of their lesser magnitude of glucose lowering, they are prescribed more commonly as an addition to another type of medicine rather than as monotherapy: Metformin: First-line therapy that decreases hepatic glucose output

This simplified dosing regimen may enhance patient compliance and treatment outcomes

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The problem starts when you reach for the bigger can or stack your sources without counting

Effect of Sex There are no differences in the body surface area adjusted unbound clearance between males and females (4.8 0.17 and 4.7 0.07 L/hr per 1.73 m 2, respectively)