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Although we have long known that A1C targets are not effective, this guideline recommends focusing completely on cardiovascular and renal risk as long as A1C is less than 9%

Note: Can cause water retention and increased cortisol (more than Ipamorelin)

Peripheral levels of IGF-1 both pre-stroke and in the sub-acute phases after stroke are inversely correlated with post-stroke recovery Decreased levels of IGF-1 have been shown to be associated with better functional outcome after stroke [24]

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Despite promising preclinical evidence of CSC suppression across multiple tumor types, its clinical utility has been limited by on-target effects on hematopoietic progenitor cells, raising safety concerns over sustained telomerase inhibition