Niacinamide can occasionally cause a mild flushing sensation at the injection site, which is harmless and temporary
Gojkovic, S., Krezic, I., Kasnik Kovac, K., Malekinusic, D., Vrdoljak, B., & Kolovrat, M
Keep in mind that humans are not rats
10.1186/1471-2202-8-S2-S2 BMC Neurosci
Biomolecules 12(4):580 Zhu Y, Jian X, Chen S, An G, Jiang D, Yang Q, Zhang J, Hu J, Qiu Y, Feng X, Guo J, Chen X, Li Z, Zhou R, Hu C, He N, Shi F, Huang S, Liu H, Li X, Xie L, Zhu Y, Zhao L, Jiang Y, Li J, Wang J, Qiu L, Chen X, Jia W, He Y, Zhou W (2024) Targeting gut microbial nitrogen recycling and cellular uptake of ammonium to improve bortezomib resistance in multiple myeloma
At low pH, the MeCbl cofactor adopts the base-o form in which the axial nitrogenous ligand is replaced by a water molecule