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Therefore, the intracellular GSH/GSSG ratio is commonly used to assess oxidative homeostasis within the cell

[DOI] [PubMed] [Google Scholar] 81.Vidal M, Cusick ME, Barabasi AL

In the area of the posterior pole of the fundus, there are protruding gray formations obscuring the optic nerve head

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GSH undergoes thiol-disulfide exchange in a reaction catalyzed by thiol-transferase as follows: Since this reaction is a reversible reaction, the equilibrium is determined by the redox state of the cell, which depends on the concentrations of GSH and GSSG (proportional to the log of [GSH] 2 /[GSSG]) (Lu, 1999a)