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P.VaghelaD

While both peptides promote angiogenesis, they accomplish this through different molecular routes

Glucose and insulin dynamics

Under normal conditions, HIFs are hydroxylated by the hydroxylase family in an oxygen-dependent manner, which leads to a substantial reduction in the transcriptional activity of HIFs, whereas under hypoxic conditions, the hydroxylate activity is inhibited, and HIFs accumulate in the cytoplasm

MIA, maternal immune activation

doi: 10.3389/fchem.2025.1536858 Received 29 November 2024 Accepted 27 January 2025 Published 19 March 2025 Volume 13 - 2025 Edited by Federica Aureli, National Institute of Health (ISS), Italy Reviewed by Eric Deconinck, Sciensano (Belgium), Belgium Maria Cristina Gaudiano, National Institute of Health (ISS), Italy Updates Copyright 2025 Blazewicz, Poplawska, Daniszewska, Piorunska and Karynski