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10.1210/en.2008-1479 42 HayesM

The effect of long-term homocysteine-lowering on carotid intima-media thickness and flow-mediated vasodilation in stroke patients: a randomized controlled trial and meta-analysis

whilst no confirmed causal link has been established , this warrants open discussion

This is not routinely recommended for all people with type 2 diabetes but may be advised in specific circumstances

This means: Weeks 1-4: 2.5mg weekly Weeks 5-8: 5mg weekly Weeks 9-12: 7.5mg weekly (if escalation continues) Weeks 13-16: 10mg weekly Weeks 17-20: 12.5mg weekly Week 21+: 15mg weekly (maximum research dose) Not every protocol reaches the maximum dose

While the test does not directly assess NSAID sensitivity, understanding your individual GLP-1 pathway can inform your provider's recommendations for pain management, as patients with higher gastrointestinal sensitivity may need more caution with NSAIDs