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However, the contributions of the peripheral nervous system and the CNS in the mediation of the anorexic effects of the GLP-1RAs is still not completely understood [23]

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And they wanted to understand if it was more than a coincidence

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Participants lost an average of 10-15% of their body weight over the course of a year, and many showed improvements in blood pressure and cholesterol levels

[55] demonstrated that obese subjects presented increased activation in appetite and reward-related brain areas in response to food images