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To further investigate the transcriptional changes in functionally coordinated genes, Gene Set Enrichment Analysis (GSEA) 33 was performed using the Kyoto Encyclopedia of Genes and Genomes (KEGG) functional gene sets available in MSigDB ( The top 10 downregulated and 10 upregulated KEGG gene sets in GLA-mutant Fabry kidney organoids compared with WT kidney organoids are shown in Supplementary Table 2

In addition to their anti-HTN effects, many of the mentioned plants exhibit antioxidant, antiinflammatory, antiproliferative, and other beneficial activities

Conditions under which glutathione disrupts the biofilms and improves antibiotic efficacy of both ESKAPE and non-ESKAPE species

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Mitochondrial Protection The mitochondrial pool of glutathione is separate from the cytosolic pool and is particularly vulnerable to depletion

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