For some, it can take up to two weeks to feel the full effects
This phenomenon was observed in the famous Minnesota Starvation Diet, where men in WW2 concentration camps were starved and were noted to have intrusive food thoughts, among many other side effects
But a study by Canadian scientists published in Jama Ophthalmology has found that after six months of use GLP-1 RAs are associated with double the risk of older people with diabetes developing neovascular age-related macular degeneration compared with similar patients not taking the drugs
These drugs mimic the effects of the naturally occurring GLP-1 hormone, which is produced in the small intestine and plays a crucial role in regulating insulin secretion, glucose homeostasis, and appetite
Some individuals may have a genetic predisposition to hair loss that is exacerbated by the use of certain supplements, including glutathione
Moreover, the strong effects observed in animal studies have not always translated to humans (Slykerman et al., 2025)
