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The peptide upregulates expression of epidermal growth factor, hepatocyte growth factor, and vascular endothelial growth factor among others

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the bronchodilator ipratropium and the calcium channel blocker verapamil) have been proposed as substrates 19,20 , though these compounds, alongside a number of other cationic drugs, were shown to be poor substrates for OCTN2 21

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By adding the peptide-induced pulse on top of this, you can achieve a profound synergistic effect