A single D208N mutation introduces PDH activity in a spirochaetes TyrA a To test if the acidic residue at the corresponding 222 position in spirochaetes SsTyrA a is involved in its substrate specificity, the D208N mutation that converts the active site acidic residue into a non-acidic residue was introduced in SsTyrA
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PMID: 35052554
We also review therapeutic approaches for enhancing GSH status
Boosting NAD + levels through the PreissHandler pathway is achievable through NA supplementation 28,29
P., Kamimura A
