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Endogenously, GLP-1 is secreted by intestinal L cells in response to food, and has multiple roles: enhancing insulin secretion (in a glucose-dependent way), reducing glucagon secretion, slowing gastric emptying, increasing feelings of fullness/satiety, and improving glucose disposal in peripheral tissues

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For general gut health maintenance and mild gastrointestinal support, standard doses typically range from 1,500 mg to 5,000 mg (1.5 to 5 grams) per day