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Legumainan asparaginyl endopeptidase with unclear roles in renal homeostasisalso modulates this pathway: Legumain knockout reduced I/R-induced renal ferroptosis and increased GPX4 protein (but not mRNA) levels

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doi:10.4093/dmj.2025.0242 60

Research published in Nature Communications detailed the structural and dynamic features of how cagrilintide binds to these receptors

244 Conclusions and future perspectives Once inside a cell, cysteine can have different fates, including the synthesis of glutathione or proteins, oxidative or non-oxidative catabolism, and reversible post-translational protein modification, each of which can contribute to the development and progression of cancer (Fig