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Metformin activates AMP-activated protein kinase in primary human hepatocytes by decreasing cellular energy status

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doi: 10.1371/journal.pone.0099835 129 ZhouGXLiXYZhangQZhaoKZhangCPXueCHet al

To assign cell populations to spatial locations within the AP, NTS and DMV, we used Molecular Cartography, a spatial transcriptomics platform based on single-molecule fluorescence in situ hybridization, to profile 13 DVC sections from four lean rats (Fig

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Abnormalities in iron homeostasis in brain tissue can induce massive production of ROS in brain cells, ultimately causing catastrophic oxidative damage to sensitive subcellular structures 60