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Stem Cells Dev (2013) 22:326170.10.1089/scd.2013.0242 10 FrancisNWongSHHampsonPWangKYoungSPDeignerHPet alLactoferrin inhibits neutrophil apoptosis via blockade of proximal apoptotic signaling events

Prior to the trial, the older cohort exhibited severe intracellular glutathione deficiency, massive oxidative stress, and impaired mitochondrial function compared to young, healthy controls

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TrimethylamineNoxide induces vascular inflammation by activating the NLRP3 inflammasome through the SIRT3SOD2mtROS signaling pathway

But the leap from animal models to human outcomes is large