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Vomiting Diarrhea Constipation Indigestion Decreased appetiteLess Common but Serious Side Effects: Hypoglycemia (low blood sugar): Especially when used in combination with other diabetes medications like insulin

The neurochemical effects of GLP-1 medications on reward pathways appear to be dose-dependent and reversible

In glycemic control clinical trials, the risk of hypoglycemia was increased when semaglutide injection or tablet was used concomitantly with insulin or an insulin secretagogue (e.g., sulfonylurea)

He also pointed to a study in animals suggesting that GLP-1 drugs may reduce the number of proteins that are responsible for transferring nutrients from the mother to the fetus, often found in the placenta

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