Side effects that some people using semaglutide experience include: Gastrointestinal issues, such as nausea, vomiting, diarrhea, constipation, heartburn, burping and stomach pains Less often, the following more serious side effects can also occur: Fatigue Rash and itching Swelling of the legs and hands Vision changes Fainting or dizziness Allergic reactions Higher risk for pancreatitis (inflammation of the pancreas) Hypoglycemia (especially when combined with other diabetes medications) Possible risk of increased heart rate and thyroid tumors, including cancer (a warning required by the FDA) If you experience any of these symptoms, call your doctor right away and get emergency medical treatment if the symptoms become severe
If you have any concerns or questions about your treatment, always consult your GP or specialist for personalised guidance
Making simple mistakes, like drinking coffee too soon after your dose or choosing a low-quality supplement can waste your money and delay results
If you miss more than 4 weeks, restart at a lower dose than where you left off, typically dropping back one or two dose tiers to allow readaptation
Alli as a pharmacy medicine) Headache and fatigue reported with several weight loss agents Injection site reactions relevant to injectable medications such as semaglutide and liraglutide Reduced appetite and early satiety often considered a therapeutic effect but can contribute to nausea According to EMA assessment reports and MHRA-approved SmPCs, gastrointestinal side effects are the most common reason patients discontinue GLP-1 receptor agonist therapy
Replace lost fluids Usually improves as body adapts Injection Site Reactions Rotate injection sites (abdomen, thigh, upper arm) Let alcohol swab dry completely before injecting Ensure medication is at room temperature Inject slowly and steadily When to Seek Medical Attention Contact a healthcare provider immediately if you experience: Severe abdominal pain that doesn't go away Symptoms of pancreatitis (severe upper abdominal pain radiating to back) Signs of allergic reaction (swelling, difficulty breathing) Persistent vomiting leading to dehydration Visual changes (rare: diabetic retinopathy worsening in diabetes patients) Compounded Semaglutide Considerations Due to brand-name shortages and high costs, many people obtain compounded semaglutide from 503A or 503B compounding pharmacies
