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Until targeted gene-specific therapies become widely available and effective for all MC4R variants, GLP-1 RAs represent a crucial therapeutic tool, offering a path toward significant clinical benefit for patients grappling with this challenging form of monogenic obesity

Oncogene 30 , 29862996 (2011)

Time spent on ineffective treatments is time that could be spent on evidence-based options with demonstrated outcomes

What does the clinical evidence say about GLP-1 timing

Beyond the Cardiovascular Effects of Glucagon-like Peptide-1 Receptor Agonists: Body Slimming and Plaque Stabilization