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This requires immediate hospitalization and assistance with breathing, usually via a ventilator

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Two randomized, double-blind, placebo-controlled studies with 50 and 53 participants tested a fine layer of 5% cysteamine cream on the face at night, leaving it up to 3 hours for 16 weeks, achieving reductions of the MASI by 50% and 59%, respectively [46, 47]

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I 2 = 90.3 %