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Artemisinin markedly diminishes the inflammatory response, primarily through downregulation of NF-B activity and its downstream cytokines, chemokines, and gene expressions, while also extending its regulatory effects to encompass transcription factors such as mTOR, activator protein-1 (AP1), HIF-1, STAT, and NRF-2, thereby enhancing its anti-inflammatory and immunomodulatory capabilities (240)

These findings help inform how targeting multiple hormone pathways may affect appetite regulation and metabolism in controlled study settings

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GLP-1 (Glucagon-like peptide-1) and GLP-2 (Glucagon-like peptide-2) are hormones produced by the L-cells of the small intestine, primarily in response to the presence of food

Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH

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