semaglutide and kidney failure Recent medical milestones include the **2025 FDA approval** of **Ozempic ( semaglutide)** specifically to slow the progression of chronic disease (CKD) in patients with type 2 diabetes. Clinical trials showed a **24% Cardio-kidney-metabolic protective effects of semaglutide

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OBrien Kidney Center at Yale (P30DK079310)

The findings were published in JAMA Internal Medicine on January 20, showing that glucagon-like peptide-1 (GLP-1) receptor agonists like Ozempic carry an 8.2% higher risk of chronic kidney disease than sodium-glucose cotransporter-2 (SGLT2) inhibitors

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Therefore, if there is less than a 5% to 10% reduction in pre-treatment weight after 12 weeks of medication, individuals may face the risks of side effects and increased costs without benefiting from the treatment