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Metformin and other drugs used for T2DM, like the SGLT2 inhibitors, may also reduce hyperglycemia-induced elevated endothelial ROS, independent of negative effects on complex 1, such as via inhibition of NADPH oxidase or blocking the entry of glucose into the endothelium (107109, 187, 188) ( Table 2 )

A., Barsanti, J

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DHA is selectively incorporated into retinal and neuronal cell membranes (91, 92), suggesting it plays important roles in vision and nervous system function