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Optimizing single-agent therapy often represents the most prudent initial approach

Create a relaxing bedtime routine dim the lights, avoid screens the last hour if possible (blue light can disturb melatonin production)

Corrective measures should be taken if the cause is preventable or reversible

In some women who take Ozempic, the rapid weight loss that occurs throughout the body may result in visible sagging of the labia or vagina because of overall fat and volume loss

For Ozempic, this typically starts at 0.25 mg once weekly for 4 weeks, then increasing to 0.5 mg, with further increases as needed

Systematic review registration: identifier PROSPERO (CRD42022337099)