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It is stated that nevi with high-grade dysplasia and/or with additional genetic alterations such as TERT promoter mutation should be considered for complete excision (62)

Itaconate is an Anti-Inflammatory Metabolite That Activates Nrf2 via Alkylation of KEAP1

Harvard Medical School Division of Sleep Medicine

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Furthermore, cysteine depletion triggers extensive ferroptosis reactions compared with GSH deletion (104)