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A similar rationale underpins regimens for Friedreichs ataxia, where riboflavin plus antioxidants (CoQ10, -lipoic acid) counter mitochondrial ironsulfur-cluster loss and free-radical injury, offering symptom relief beyond monotherapy (79, 80)

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Effect of sleep changes on health-related quality of life in healthy children: a secondary analysis of the DREAM crossover trial

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