The cellular uptake and anti-proliferative effects of nanoparticles induced significant apoptosis in TMZ-resistant U87MG cells, with a lower IC50 value (17.8 ng/mL) compared to free DTX, which was about 33 ng/mL
Therefore, amino acid metabolism plays an important role in maintaining tumor proliferation and homeostasis
Most side effects, like dryness and redness, improve within a few weeks as your skin adjusts
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These ROS not only harm cellular structures but also further impair the BBB by degrading tight junction proteins and promote endothelial death (Fernndez et al., 2020)