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Fang B., Zhou C., Rao X., European Journal of Medicinal Chemistry , 2010 , 45 , 4388

Persistent coxsackievirus B infection and pathogenesis of type 1 diabetes mellitus

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Common Degradation Pathways Deamidation of asparagine residues Methionine oxidation Peptide backbone hydrolysis Acyl chain hydrolysis Isomerization reactions Advanced LC-MS methods allow researchers to identify the exact location of degradation events within the peptide sequence

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