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Weight loss may occur, though this can be difficult to interpret in patients using GLP-1 agents for weight management

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The regain is not inevitableresearch demonstrates that people who establish sustainable eating patterns, maintain regular physical activity, and address underlying metabolic factors often keep 30-50% of their initial weight loss even after stopping the medication

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A landmark 2025 study published in PNAS highlighted that both Long COVID and ME/CFS are fundamentally driven by elevated oxidative stress and mitochondrial damage in immune cells